What Are Kratom Alkaloids
What Are Kratom Alkaloids
You have probably heard of kratom and its many properties, but do you know kratom alkaloids, the compounds responsible for the plant's popularity? This article discusses all you need to know about these alkaloids.
Kratom alkaloids are chemical compounds found in the leaves of the kratom plants. These compounds have structural differences, meaning that they interact with the body in different ways.
Over 40 alkaloids are present in kratom leaves, with mitragynine and 7-hydroxymitragynine being the most prominent ones. Their popularity is down to the fact that they bind most easily with the receptors in our bodies. However, this does not mean that the other alkaloids are inferior.
The concentration levels in these alkaloids are unique depending on age and the harvest timing, among other factors. How you prepare this product will also determine the alkaloid yield you get from it. For example, traditionally prepared kratom tea yields a better value of mitragynine, the most abundant alkaloid in kratom.
Here is a look at some of the most common kratom alkaloids
Mitragynine is the primary alkaloid in kratom, making over 70% of the alkaloid content in Kratom leaves. Its prominences make it a center subject of constant research and studies in various disciplines. It is an indole that acts as antidiarrheal, antimalarial, analgesic, and antitussive.
Some studies also show that it is a potential psychedelic antagonist.
Many people believe that mitragynine, being the significant component in the plant, is responsible for kratom's medical effect.
This compound is an excellent analgesic and a potential mu-opioid agonist. It is the second most prominent compound in the plant. Because of this, experts believe it is also responsible for the medicinal properties of kratom.
7-hydroxymitraginine is a partial agonist with the same chemical similarities as mitragynine. Its concentration greatly varies depending on the harvest time, the strain, and the dying processes. It is also a highly potent compound and attracts several studies and research, with experts believing that it could be the key to some of the effects connected to herbal remedies.
Paynantheine is the second most abundant compound in kratom, with about 6.6% to 7% of the total share. It, however, comes third as the most active alkaloid in the plant.
Research into its effects has only just begun, but researchers have already determined that this compound is a great smooth muscle relaxant. Mitraphylline
Mitraphylline and every other remaining compound in this plant represent less than 1% of the total alkaloid count. But, they still have a significant effect.
Mitraphylline is one of the oxindole alkaloid compounds in kratom. One of its notable effects is dilating blood vessels helping in various medical conditions like hypertension and headache. It also bears the same muscle relaxing properties as paynantheine and speciogynine.
Rhynchophylline has a similar chemical structure to mitragynine but with significantly different effects. It has several medical properties, most notably its anti-inflammatory effects. Research shows that it also reduces neural damages in cases of stroke.
Other common effects include reducing fever, acting as a calcium channel broker, and contributing to kratom's antihypertension elements.